Casa Netural is situated in a historic working-class neighborhood of Matera, designed by Adriano Olivetti, in the Basilicata region of southern Italy. The area is quiet yet well-served, with supermarkets, bakeries, dairies, butchers, and grocery shops within easy reach. Guests describe it as a calm neighborhood full of bakeries, bars, and everyday services.
The famous Sassi di Matera — the UNESCO World Heritage cave dwellings — are a 15–20 minute walk away. The city itself is one of the oldest continuously inhabited settlements on Earth, and its historic center is surrounded by a canyon rich in prehistoric caves, rock churches, and natural landscapes. Matera also serves as a gateway to the wider Basilicata region, Apulia, and Calabria.